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Not that he's any more reasonable or compassionate to his boss Cuddy (Lisa Edelstein), his oncologist best friend Wilson (Tony winner Robert Sean Leonard), or his young charges Foreman (Omar Epps), Cameron (Jennifer Morrison), and Chase (Jesse Spencer). He instructs his doctors to break into patients' homes as if they're cat burglars. He does not know the meaning of the phrase "politically correct." But because he spits out insults (as if he has a mild case of Tourette's) equally to both his patients and colleagues, the latter never flinch at his constant stream of inappropriateness. When his three young doctors storm into his office to report the declining condition of a patient by blurting out, "We have rectal bleeding," House says, "What? All three of you?" To sensitive Wilson, who is trying to get some work done without being interrupted, House says, "I know you're in there. I can hear you caring." And when Foreman's father says, "My son says you're a manipulative bastard," House replies, "It's a pet name. I call him Dr. Bling." Of course House actually does care about his patients, but he views a good bedside manner as the luxury of a doctor who has a healthy patient. But dying patients with seemingly incurable diseases need something more. They need House. --Jae-Ha Kim

Lucas Scott (Chad Michael Murray), following a well-received first novel, is facing writer's block on his second effort. But he fills his days as the new head coach of his old high-school basketball team, the Ravens, aided by his old pal, Skills (Antwon Tanner). Meanwhile, Lucas' brother, Nathan (James Lafferty), is lost in a dark hole of despair after losing his dream of signing with an NBA team. Barely able to move his legs, Nathan is almost crippled in a bar fight and spends his days and nights boozing and raging around while wife Haley (Bethany Joy Galeotti) and young son Jamie (Jackson Brundage) try to survive his emotional torrents. Lucas is no longer with Peyton (Hilarie Burton), the latter having moved to Los Angeles to become a disgruntled assistant's assistant in a music recording company. Brooke (Sophia Bush), however, has hit the jackpot in New York as the celebrity founder of a designer clothes empire that has made her wealthy yet not quite free of her domineering mother (Daphne Zuniga). Everyone ends up back in Tree Hill, looking for roots and a future that involves support from one another. Friendship matters, but it doesn't inoculate this bunch from the pain of Peyton's ongoing love for Lucas (who is romantically involved with his pretty editor), or Brooke's emptiness after briefly fostering a child who then must leave her, or Nathan's slow crawl back from misery. In true One Tree Hill fashion, the characters' collective challenges come together in a critical mass during the season finale, ending with a very unusual cliffhanger involving four cell phones. --Tom Keogh

Unfortunately the DVD features no commentary and just one extra: Executive Producer Mark Wahlberg, on whom the show is based, interviews the cast and producers. The banter is interesting enough, but Wahlberg makes such a dull interviewer it's certain we won't see a talk-show host career in Vince's future. --Ellen A. Kim